產(chǎn)品名稱 A 83-01 from TOCRIS BIOSCIENCE
    產(chǎn)品貨號 2939/10
    產(chǎn)品價格 現(xiàn)貨詢價，電話：010-67529703
    產(chǎn)品規(guī)格 10 mg
    產(chǎn)品品牌 TOCRIS BIOSCIENCE
    產(chǎn)品概述
    產(chǎn)品詳情
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    Product NameA 83-01
    DescriptionPotent inhibitor of TGF-β type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC50 values are 12, 45 and 7.5 nM respectively). Blocks phosphorylation of Smad2 and inhibits TGF-β-induced epithelial-to-mesenchymal transition. Only weakly inhibits ALK-1, -2, -3, -6 and MAPK activity. More potent than SB 431542 (Cat.No. 1614). Inhibits differentiation of rat induced pluripotent stem cells (riPSCs) and increases clonal expansion efficiency. Helps maintain homogeneity and long-term in vitro self-renewal of human iPSCs. Purity 98%. MW (observed): 421.52
    Size10 mg
    Concentrationn/a
    Applicationsn/a
    Other Names3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide
    Gene, Accession, CAS #CAS: 909910-43-6
    Catalog #2939/10
    Price
    Order / More InfoA 83-01 from TOCRIS BIOSCIENCE
    Product Specific ReferencesPubMed: 20660726, 21305472, 22927969, 23324343, 23666117, 23728301, 23917481, 23935837, 24204693, 24637302, 25064463, 25437872, 25533785, 25557080, 25610469, 25634246, 25693565, 25740845, 25822089, 25870291, 26332312, 26354680, 26365514, 26455412, 26460009, 26677983, 26797458, 27133794, 27320041, 27819344, 28165492, 28669603, 29168693, 29358044
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