A DNA sequence encoding the mouse CD79A (NP_031681.2) (Met1-Arg137) was fused with a polyhistidine tag at the C-terminus, constructed the plasmid 1; A DNA sequence encoding mouse CD79B (NP_031681.2) (Met1-Asp158) was fused with a polyhistidine tag at the C-terminus, constructed the plasmid 2. The two plasmids were co-expressed and the mouse CD79A & CD79B heterodimer was purified.