產(chǎn)品名稱 TMI 1 from TOCRIS BIOSCIENCE
    產(chǎn)品貨號(hào) 5960/50
    產(chǎn)品價(jià)格 現(xiàn)貨詢價(jià),電話:010-67529703
    產(chǎn)品規(guī)格 50 mg
    產(chǎn)品品牌 TOCRIS BIOSCIENCE
    產(chǎn)品概述
    產(chǎn)品詳情
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    Product NameTMI 1
    DescriptionAdam 17 (TACE) and MMP inhibitor (IC50 values are 3, 4.7, 6.6, 8.4, 12, 26 and 26 nM for MMP-13, MMP-2, MMP-1, ADAM 17, MMP-9, MMP-7 and MMP-14, respectively). Suppresses TNF-α production in an acute LPS-mouse model. Reduces severity score in an in vivo model of rheumatoid arthritis. Displays selective cytotoxicity to tumor cells and cancer stem cells in vitro. Induces tumor apoptosis in a breast cancer in vivo model. Orally bioavailable. Purity 98%. MW (observed): 398.49
    Size50 mg
    Concentrationn/a
    Applicationsn/a
    Other Names(3S)-4-[[4-(2-Butyn-1-yloxy)phenyl]sulfonyl]-N-hydroxy-2,2-dimethyl-3-thiomorpholinecarboxamide
    Gene, Accession, CAS #CAS: 287403-39-8
    Catalog #5960/50
    Price
    Order / More InfoTMI 1 from TOCRIS BIOSCIENCE
    Product Specific Referencesn/a
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