The Eagle Biosciences muscarinic cholinergic receptor 1 (M1) ELISA assay kit is an antibody screening test. M1 receptor has been pre-coated onto a microtiter plate. During the first incubation the anti-muscarinic cholinergic recetor 1-antibodies of the samples are immobilized on the plate. The autoantibodies are detected with an HRP labeled anti-human IgG antibody. In the following enzymatic substrate reaction, the intensity of the color correlates with the concentration and/or avidity of anti-muscarinic cholinergic receptor 1 antibodies. Sample Types: serum. Range: 2.5 - 40 U/ml. Sensitivity: Cut-off. Time: 3.5 hours ? Muscarinic cholinergic receptors (mAChRs) are acetylcholine receptors that form G protein-receptor complexes in the cell membranes of certain neurons and other cells. The Eagle Biosciences anti-muscarinic cholinergic receptor 1 (M1)-Antibody EIA is designed for the determination of antibodies against the muscarinic cholinergic receptor 1 (M1) in serum