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Description
The antibody was affinity purified using phospho-NLRC4 (Ser-533) peptide. This antibody antibody detects a 110 kDa protein on SDS-PAGE immunoblots of PMA-differentiated THP1 human macrophages. In addition, the antibody detects a mouse recombinant phospho-NLRC4 (Ser-533) peptide, but does not detect this peptide after lambda phosphatase treatment.
Immunogen
Clone M549 was generated from a phospho-NLRC4 (Ser-533) synthetic peptide (coupled to carrier) corresponding to amino acids surrounding serine 533 in mouse NLRC4. This sequence has high homology to human and rat NLRC4, and is not homologous to sequences in other NLR family members.
Other Names
CARD12, CLAN1, IPAF, NLR family CARD domain-containing protein 4, NOD-like receptor 4