RANBP1, Recombinant, Human, aa1-201, His-Tag (RAN binding protein 1)
Description
Purity ~95% (SDS-PAGE). RAN binding protein 1, also known as RANBP1, belongs to a family of proteins that bind Ran GTPase which is essential for mRNA processing, nuclear transport, cell cycle control, mitotic spindle assembly, and postmitotic nuclear re-assembly and nuclear architecture maintenance. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). Also, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN. Source: Recombinant protein corresponding to aa1-201 of human RANBP1, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~25.8kD AA