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Description
The antibody detects an 89 kDa protein corresponding to the molecular mass of the cleaved fragment of PARP induced by staurosporine treatment of Jurkat cells. The antibody can be used to identify caspase-3 activity during apoptosis.
Immunogen
Clone 194C1439 was generated from a synthetic peptide corresponding to amino acids around the 214/215-cleavage site in human PARP. This sequence is well conserved in rat and mouse PARP, but the antibody has not been tested for these species reactivities.