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| Antigenic Specificity | Secretory Component (Soluble) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | antigen affinity purified |
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| Size | 1 mL |
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| Concentration | n/a |
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| Applications | Immunoelectrophoresis (IEP) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Tested in immunoelectrophoresis, double radial immunodiffusion and ELISA against a panel of appropriate secretions and purified Ig isotypes. The antiserum reacts with the free SC present in human secretions. In immunoelectrophoresis against human milk, using a high electro-endosmosis agar plate, free SC is precipitated in the alph-2 region. The antiserum does not react with sIgA, or with any other secretory or plasma protein |
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| Immunogen | Secretory component is present in human secretions bound to secretory IgA (sIgA) and in free form. Secretory IgA (sIgA) functions as a dimer or polymer and accounts for almost all specific mucosal antibody activity. A molecule of sIgA is made up of two molecules of IgA, one J chain and one SC (MW 65,000). The dimer IgA is transported into secretions by its binding to the SC on the epithelial cells. Under normal conditions, sIgA contains both subclasses IgA1 and IgA2, since both are capable of binding SC. SC also has an affinity for polymeric IgM. Purified free human secretory component isolated from immunoglobulin deficient milk is used for immunization. Freund's complete adjuvant is used in the first step of the immunization procedure. |
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| Other Names | n/a |
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| Gene, Accession # | n/a |
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| Catalog # | ABIN458147 |
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| Price | |
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| Order / More Info | Secretory Component (Soluble) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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