Mouse IGFBP-5, recombinant protein (Receptor Grade)
Description
Product Specifications Mouse IGFBP-5: Mouse Insulin-like Growth Factor Binding Protein-5 (mIGFBP-5) is a 252 amino acid protein that is one of the six ' A``classical' IGF binding proteins that play an important role in stabilizing and regulating the activity of IGFs in vivo. Mouse IGFBP-5 preferentially binds IGF-II and it also binds with high affinity to extracellular matrix components which protect it from proteolysis. Like human IGFBP-5, mouse IGFBP-5 has a nuclear targeting sequence. Link to Sequence.
Kiefer M. et al. (1991) Biochem. Biophys. Res. Commun. 176, 219-225 Song, H. et al. (2000) J. Mol Endocrinol. 24, 43-51 Source:Produced recombinantly in E.coli. Purified by affinity and other chromatographic steps. Purity:> 90% (by SDS PAGE) Molecular Weight:29 kDa (non-glycosylated