mouse, rat, human.predicted to work with: Saccharomyces cerevisiae
Isotype
IgG1
Format
peroxidase (HRP) conjugate
Size
50ul
Concentration
1mg/ml
Applications
IP, WB
Reviews / Ratings
If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description
Mouse Anti-PP2A alpha (methyl L309) [2A10]: Horseradish Peroxidase (HRP). This antibody specifically recognises the C-terminally methylated form of PP2A C subunit.
Immunogen
A KLH-coupled peptide with the sequence: KLH-C- A-RRTPDYFL-OMe. The c-terminal sequence (as well as the carboxy-methylation) is absolutely conserved from human, mouse to yeast
Other Names
PP2A alpha, PP2A C, PP2A-alpha, PP2AA_HUMAN, PP2Ac, PP2CA, PPP2CA, Protein phosphatase 2, catalytic subunit, alpha isoform, Replication protein C
Benziane B et al. Activation of AMP-activated Protein Kinase Stimulates Na ,K -ATPase Activity in Skeletal Muscle Cells. J Biol Chem 287:23451-63 (2012). WB PUBMED Li T et al. Microcystin-LR (MCLR) Induces a Compensation of PP2A Activity Mediated by a4 Protein in HEK293 Cells. Int J Biol Sci 7:740-52 (2011). WB ; Human PUBMED Finnegan S et al. A stress survival response in retinal cells mediated through inhibition of the serine / threonine phosphatase PP2A. Eur J Neurosci : (2010). WB ; Mouse PUBMED Hombauer H et al. Generation of active protein phosphatase 2A is coupled to holoenzyme assembly. PLoS Biol 5:e155 (2007) PUBMED Sontag E et al. Downregulation of protein phosphatase 2A carboxyl methylation and methyltransferase may contribute to Alzheimer disease pathogenesis. J Neuropathol Exp Neurol 63:1080-91 (2004) PUBMED Sontag E et al. Altered expression levels of the protein phosphatase 2A ABalphaC enzyme are associated with Alzheimer disease pathology. J Neuropathol Exp Neurol 63:287-301 (2004) PUBMED Fellner T et al. A novel and essential mechanism determining specificity and activity of protein phosphatase 2A (PP2A) in vivo. Genes Dev 17:2138-50 (2003) PUBMED