A lignan with anti-inflammatory and anticancer activities; inhibits LPS-induced NO production in BV-2 cells (IC50 = 20.5 μM); inhibits ERK1 and ERK2 (IC50s = 87 and 16.5 nM, respectively); suppresses migration and decreases markers of EMT in vitro; inhibits proliferation, halts the cell cycle, and induces apoptosis in PC3 and DU145 cells at 50 and 100 μM; reduces tumor growth and increases apoptosis of tumor cells in a PC3 prostate cancer mouse xenograft model at 50 μmol/kg