Chromosome 12 Open Reading Frame 57 (C12orf57) (Active) protein
Description
Mouse C10 belongs to the CC chemokine family and is expressed in myelopoietic bone marrow cultures when stimulated with GM-CSF, M-CSF, IL3 or IL4. It signals primarily through the CCR1 receptor. C10 is chemotactic for B cells, CD4+ T cells, monocytes and NK cells and also exhibits powerful suppressive activity on colony formation by different lineages of hematopoietic progenitors. The C10 contains the four highly conserved cysteine residues present in CC chemokines. The mature protein contains 95 amino acid residues. Alternative Names: C-10, MRP-1 protein, C10, C-10 protein, C 10, CCL6 protein, C 10 protein, C-10 protein