A broad-spectrum aminoglycoside antibiotic; active against Gram-positive and Gram-negative bacteria including B. subtilis, S. aureus, E. coli, and P. aeruginosa, among others (MICs = 0.01-0.75 μg/ml); protective against Gram-positive and Gram-negative bacterial infections in mice (PD50s = 0.5-6 mg/kg)