A natural macrocyclic antibiotic that inhibits RNA polymerase with selectivity for Gram-positive bacteria over Gram-negative bacteria (IC50s = 0.4 and 6 μM, respectively); has potent antibacterial activity against most Gram-positive bacteria and effectively targets the Gram-positive C. difficile (MIC = 12 ng/ml)
Size
100 mg
Concentration
n/a
Applications
n/a
Other Names
Clostomicin B1|Difimicin|Lipiarmycin|OPT-80|PAR-101|Tiacumicin B