A specific inhibitor of class I α-1,2-mannosidase (IC50 = 20 mM), a key enzyme for N-glycan processing in the endoplasmic reticulum and Golgi; inhibiting α-1,2-mannosidase with 1-Deoxymannojirimycin generates N-linked oligosaccharides with high mannose content, preventing proteasomal degradation of misfolded proteins
Size
25 mg
Concentration
n/a
Applications
n/a
Other Names
class I α1,2-mannosidase ER α-mannosidase I Man9GlcNAc2-specific processing α-mannosidase N-linked oligosaccharide carbohydrate research misfolded protein degradation cancer antiviral 84444-90-6 biochemical inhibit inhibitor enzyme glycan endoplasmic reticulum Golgi target translocation proteasome mannose prevent glycoprotein anti-cancer viral therapy therapies