2-Methyl-5-hydroxytryptamine is a 5-HT3 agonist (Ki = 1200 nM) and potent 5-HT6 ligand (Ki = 46 nM). Recently, this has been used as one of the components of the chemical cocktails used for reprogramming of mouse somatic cells toward pluripotent cells in the absence of Oct4. MW: 226.71. Purity ≥98% by HPLC