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Description
Rabbit IgG polyclonal Picoband? antibody for KMT6/EZH2 detection. Tested with WB, Direct ELISA in Human;Mouse;Rat. No cross reactivity with other proteins. Enhancer of zeste homolog 2 (EZH2) is a histone-lysine N-methyltransferase enzyme encoded by EZH2 gene. It is mapped to 7q36.1. This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.
Immunogen
E.coli-derived human KMT6/EZH2 recombinant protein (Position: E22-T345).