Con A-Sepharose is a solid-phase lectin that binds to glycoproteins that contain alpha-D-glucosyl or alpha-D-mannosyl groups. This binding requires Ca2+ and Mn2+ co-factors. Refrigerate for short term use or freeze for long term storage. Avoid repeated freeze/thaw cycles. Product is shipped FedEx overnight on ice packs within continental US. The first item is $30, additional items are shipped at no additional shipping costs.