A DYRK1B inhibitor (IC50 = 17 nM) that demonstrates 5-fold and 110-fold selectivity against the related family members DYRK1A and DYRK2, respectively; used as a probe to elucidate the mechanism of DYRK1B regulation of cell cycle progression
Size
5 mg
Concentration
n/a
Applications
n/a
Other Names
AZ-191 signal transduction metabolic syndrome intracellular signaling cancer biochemical inhibitor kinase cell cycle DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B selective