產(chǎn)品名稱 AC 710 from TOCRIS BIOSCIENCE
    產(chǎn)品貨號(hào) 5013/10
    產(chǎn)品價(jià)格 現(xiàn)貨詢價(jià)，電話：010-67529703
    產(chǎn)品規(guī)格 10 mg
    產(chǎn)品品牌 TOCRIS BIOSCIENCE
    產(chǎn)品概述
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    Product NameAC 710
    DescriptionPotent PDGFR family inhibitor (IC50 values are 1.2, 2, 7.7 and 10.5 nM for KIT, FLT3, PDGFRβ and CSF1R respectively; Kd = 1.3 nM for PDGFRα). Exhibits >30-fold selectivity over a panel of other kinases and exhibits no activity against cytochrome P450. Causes tumor regression of leukemia cell xenografts in mice. Also reduces joint swelling and inflammation in a mouse model of collagen-induced arthritis. Orally active. Purity 99%. MW (observed): 562.7
    Size10 mg
    Concentrationn/a
    Applicationsn/a
    Other NamesN-[4-[[[[5-(1,1-Dimethethylethyl)-3-isoxazolyl]amino]carbonyl]amino]phenyl]-5-[(1-ethyl-2,2,6,6-tetramethyl-4-piperidinyl)oxy]-2-pyridinecarboxamide
    Gene, Accession, CAS #CAS: 1351522-04-7
    Catalog #5013/10
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    Order / More InfoAC 710 from TOCRIS BIOSCIENCE
    Product Specific ReferencesPubMed: 29571051
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