產(chǎn)品名稱 NF449 (sodium salt) from CAYMAN CHEMICAL COMPANY
    產(chǎn)品貨號 13324-1
    產(chǎn)品價格 現(xiàn)貨詢價，電話：010-67529703
    產(chǎn)品規(guī)格 1 mg
    產(chǎn)品品牌 CAYMAN CHEMICAL COMPANY
    產(chǎn)品概述
    產(chǎn)品詳情
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    Product NameNF449 (sodium salt)
    DescriptionAn analog of suramin that selectively inhibits P2X1 receptors (pIC50 = 6.3); selectively antagonizes the Gsα-subunit G protein, which suppresses the association rate of GTPγS binding to Gsα-s, inhibits the stimulation of adenylyl cyclase activity, and blocks G protein coupling to certain GPCRs
    Size1 mg
    Concentrationn/a
    Applicationsn/a
    Other Names389142-38-5 suramin inhibitors P2X1 platelets aggregations thromboembolism G-proteins antagonists inhibits inhibitions G proteins Gproteins NF-449 NFs 449 analogs 11126 purinergic potent potency decreases intravascular platelets aggregation mouse mice models systemic antagonism Gsa Gsα Gsalpha Gs.alpha. subunits adenylyl cyclase activity GPCRs P2Y1 P2Y2 P2Y11 selective supresses supression associations rates binding binds stimulation stimulates blocks coupling active
    Gene, Accession, CAS #CAS: 627034-85-9
    Catalog #13324-1
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    Order / More InfoNF449 (sodium salt) from CAYMAN CHEMICAL COMPANY
    Product Specific Referencesn/a
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