A mast cell tryptase inhibitor (Ki = 7.1 μM for human recombinant enzyme); reduces maximum contractile response to histamine in isolated bronchial tissue from ovalbumin-sensitized guinea pigs at 1 μM; reduces airway resistance and increases dynamic lung compliance in A. suum antigen-challenged pigs at 5 mg in 1 ml of water, aerosol; reduces collagen content and expression of PAR-2 and α-SMA in rat liver in a model of bile duct ligation-induced liver fibrosis