GOT1 is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, which participate in AA metabolism and the urea and tricarboxylic acid cycles. Both enzymes are homodimeric and show close homology Synonyms: EC 2.6.1.1, Aspartate aminotransferase 1, Transaminase A, GIG18