(±)17-HDHA is an autoxidation product of DHA in vitro.{7479,7491} It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes.{7480,7490,7492} 17(S)-HDHA can be produced by enzymatic oxidation of DHA using soybean LO and is the putative product of mammalian 15-LOs.{7492} 17(S)-HDHA is an inhibitor of U-46619-induced rabbit and rat aortic smooth muscle contraction with IC50 values of 4.9 and 7.2 μM, respectively.{7481} (±)17-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant PUFA.
Size
25 μg
Concentration
n/a
Applications
n/a
Other Names
(±)17-HDoHE|17-hydroxy Docosahexaenoic Acid|17-hydroxy DHA