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Description
NBPF Pan Polyclonal Antibody. This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, mental retardation, congenital heart dis
Immunogen
n/a
Other Names
Neuroblastoma breakpoint family member 1, Neuroblastoma breakpoint family member 9, Neuroblastoma breakpoint family member 10, Neuroblastoma breakpoint family member 12, Neuroblastoma breakpoint family member 14, Neuroblastoma breakpoint family member 16, Neuroblastoma breakpoint family member 16, Neuroblastoma breakpoint family member 20, NBPF1, NBFP9, NBFP10, NBFP12, NBFP14, NBFP15, NBFP16, NBFP20