Recombinant Human TRAF family member-associated NF-kappa-B activator (TANK), partial
Description
Purity > 90% as determined by SDS-PAGE. MW: 40.8kDa. Partial: 1-119aa. N-terminal GST-tagged. Homo sapiens (Human). Adapter protein involved in I-kappa-B-kinase (IKK) regulation which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity. Acts as a regulator of TRAF function by maintaining th in a latent state. Blocks TRAF2 binding to LMP1 and inhibits LMP1-mediated NF-kappa-B activation. May control negatively TRAF2-mediated NF-kappa-B activation signaled by CD40, TNFR1 and TNFR2.