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Description
Rabbit Anti-LDLR Recombinant Antibody (CBYCL-208). Provided herein is a Rabbit monoclonal antibody against Human LDLR. The antibody can be used for immunoassay techniques, such as ELISA, WB. The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis take