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Description
Mouse Anti-LDLR Recombinant Antibody (CBYJL-1381). Provided herein is a Mouse monoclonal antibody, which binds to Low Density Lipoprotein Receptor (LDLR). The antibody can be used for immunoassay techniques, such as WB. The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cho
Immunogen
Recombinant human LDLR produced in the 293E cell line.