產(chǎn)品名稱 GW 803430 - GW 3430
產(chǎn)品貨號 Axon 1569 CAS [515141-51-2] MF C25H24ClN3O3SMW 481.99 Purity: 98% Soluble in DMSO Description Selective, non-peptide antagonist at the melanin concentrating hormone receptor 1 (MCH1 aka MCH R1). In animal studies it has anxiolytic, antidepressant and anorectic effects References Certificates Categories Extra info DR Gehlert?et al. Preclinical evaluation of melanin-concentrating hormone receptor 1 antagonism for the treatment of obesity and depression. J. Pharmacol. Exp. Ther. 2009, 329 (2), 429–438. ? SL Able et al. Localisation of melanin-concentrating hormone receptor 1 in rat brain and evidence that sleep parameters are not altered despite high central receptor occupancy. Eur. J. Pharmacol. 2009, 616(1-3), 101-106. ? S Chaki?and K Kanuma. Neuropeptide receptors: Novel therapeutic targets for depression and anxiety disorders. Drugs Fut. 2007, 32(9), 809. Certificate of Analysis Material Safety Data Sheet CNS MCH1 Endocrinology A5 MCH1 antagonist Chemical name 6-(4-Chloro-phenyl)-3-[3-methoxy-4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-3H-thieno[3,2-d]pyrimidin-4-one Parent CAS No. [515141-51-2] Order Size Unit Price Stock 5 mg €85.00 In Stock
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GW 803430 - GW 3430

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 1569

CAS [515141-51-2]

MF C25H24ClN3O3S
MW 481.99

  • Purity: 98%
  • Soluble in DMSO

GW 803430

Description

Selective, non-peptide antagonist at the melanin concentrating hormone receptor 1 (MCH1 aka MCH R1). In animal studies it has anxiolytic, antidepressant and anorectic effects
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