Glyco-gene microarray is a focused oligonucleotide microarray containing all of the cloned glyco-genes. It is high throughout technique to screen and detect the changes of transcription and expression levels of the glycan related genes such as glycan-binding proteins, glycosyltransferases, glycosylhydrolases, carbohydrate transporters, etc. It allows the analysis of RNA samples on a highly annotated custom gene microarray. The glyco-gene microarray is developed using Affymetrix technology. It contains probe sets to monitor the expression of approximately 2000 human and mouse transcripts and can also be custom-designed.