There are two popular models of how legends fit to their specific substrate: the induced fit model and the lock and key model. Residues in the binding site interact with the ligand by forming hydrogen bonds, hydrophobic interactions, or temporary van der Waals interactions to make a protein-ligand complex. Protein ligand binding site prediction can help us to well understand the binding mechanism between the ligand and protein molecule, and so aid drug discovery. Now, bioinformaticians at Creative Proteomics are proud to tell you we are open to help you with Protein Ligand Binding Site Prediction Service!