Omega-3 fatty acids have been known as essential to normal growth and health since the 1930s. Omega-3 fatty acids are important for normal metabolism, coagulation, muscle function, cellular transport, and cell growth. DHA, in particular, is especially high in the retina, brain, and sperm. Omega-3 fatty acids are also used to form eicosanoids, which are important signaling molecules that have clinically relevant biological activities.