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| Product Name | Recombinant Human Gamma-aminobutyric acid receptor-associated protein-like 2 (GABARAPL2) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 40.7kDa. Full Length: 1-117aa. N-terminal GST-tagged. Homo sapiens (Human). Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1. Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirents and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore mbrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | GABA (A) receptor-associated protein-like 2Ganglioside expression factor 2; GEF-2General protein transport factor p16Golgi-associated ATPase enhancer of 16KDA; GATE-16MAP1 light chain 3-related protein |
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| Gene, Accession, CAS # | GABARAPL2, UniProt: P60520 |
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| Catalog # | RPC24034 |
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| Order / More Info | Recombinant Human Gamma-aminobutyric acid receptor-associated protein-like 2 (GABARAPL2) from BIOMATIK |
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| Product Specific References | n/a |
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