Chemokine (C-C Motif) Ligand 5 (CCL5) (Active) protein
Description
CCL5 or RANTES (acronym for Regulated upon Activation, Normal T cell Expressed and presumably Secreted), was initially discovered by subtractive hybridization as a transcript expressed in T cells but not B cells. Eosinophilchemotactic activities released by thrombinstimulated human platelets have also been purified and found to be identical to RANTES. Besides T cells and platelets, RANTES has been reported to be produced by renal tubular epithelium, synovial fibroblasts and selected tumor cells. Synonym: RANTES/ CCL5, Human. Formulation: Lyophilized from a 0.2μm filtered concentrated solution in 20mM PB, pH 7.4, 100mM NaCl.