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Description
This antibody was affinity purified with VE-cadherin (a.a. 770-781) peptide. The purified antibody detects a 140 kDa band corresponding to VE-cadherin in western blots of human endothelial cells, and this reactivity can be specifically blocked using VE-cadherin peptide (CX2235).
Immunogen
VE-Cadherin synthetic peptide (coupled to carrier protein) corresponds to amino acids 770 to 781 in human VE-cadherin. This sequence has significant homology to the conserved site in rat and mouse, and has less than 50% homology with other cadherins.