The GAGA factor is a sequence-specific DNA-binding protein, which participates in the regulation of the expression of a variety of different classes of genes in Drosophila such as many developmentally regulated genes, stress induced genes, and cell cycle regulated genes, as well as housekeeping genes. GAGA contains a C-terminal glutamine-rich domain and a highly conserved N-terminal POZ domain which is reported to be involved in self-oligomerization in a number of other POZ domain containing proteins. In case of GAGA protein, the N-terminal POZ domain mediates the formation of oligomers both in vitro and in vivo. GAGA-POZ domain was overexpressed in E. coli and purified by using conventional chromatography techniques. Alternative Names: Adf-2 protein, GAF protein, Adh transcription factor 2 protein, Transcription factor GAGA protein, GAGA factor protein, GAGA-POZ domain protein, Trithorax-like isoform A protein, TFGAGA protein, Nc70F protein, GAGA protein, Neural conserved at 70F protein, Trl protein, Trithorax-like protein protein, Trithorax like protein