ELISA, WB, IHC, IP ? WB 1:500 - 1:2000; IHC 1:50 - 1:200; IF 1:50 - 1:200
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Description
Rabbit anti-NELFE polyclonal antibody. The protein encoded by this gene is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins; however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D). The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6.