This LPS molecule is derived from the cell membrane of the gram-negative bacterium Bartonella quintana. In contrast to LPS derived from Escherichia coli, B. quintana LPS is a potent antagonist of TLR4, as it inhibited both mRNA transcription and the release of tumor necrosis factor alpha, interleukin 1 (IL1), and IL-6.
Size
10μg
Concentration
Lyophilized product in MilliQ, containing approximately 1 mg. Reconstitute the vial by pipetting 1 ml distilled or de-ionized water (Caution: vial is under vacuum). The exact protein concentration is indicated on the label.