human, mouse, rat (predicted: bovine, canine, hamster, monkey, rabbit)
Isotype
n/a
Format
immunogen affinity purified
Size
100ug (sample available)
Concentration
500ug/ml.
Applications
Flow Cytometry, IF, IHC-P, IHC-F, ICC, WB
Reviews / Ratings
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Description
Rabbit IgG polyclonal Picoband? antibody for C-terminal-binding protein 2(CTBP2) detection. Tested with WB, IHC-P, IHC-F, ICC/IF, FCM in Human;Mouse;Rat. No cross reactivity with other proteins. The E1a region of group C adenoviruses encodes 2 nearly identical proteins that are largely responsible for the oncogenic properties of adenoviruses. The CTBP1 protein binds to the C-terminal half of these E1A proteins. It's predicted that CTBP2 is a 445-amino acid protein and it is 72% identical to CTBP1. The CTBP2 gene is mapped to chromosome 10q26.13. CTBP2 is a mammalian corepressor that targets diverse transcriptional regulators. It bounds the short medial portion of delta-EF1 containing the PLDLSL motif and it enhances transrepression activity of delta-EF1.
Immunogen
E.coli-derived human CTBP2 recombinant protein (Position: H321-Q445). Human CTBP2 shares 99.2% and 98.4% amino acid (aa) sequence identity with mouse and rat CTBP2, respectively.