Transforming Growth Factor-Alpha, human, recombinant protein
Description
Product Specifications Human Transforming Growth Factor-Alpha, recombinant: Human Transforming Growth Factor-Alpha (TGF-alpha) is a non-glycosylated, single chain, 50 amino acid polypeptide which is a member of the Epidermal Growth Factor (EGF) family of proteins. It promotes the proliferation and differentiation of cell types displaying the EGF receptor. The biological effects of human TGF-alpha are likely to be mediated by autocrine and paracrine mechanisms in adult and embryonic cells as well as in a variety of tumors and retrovirally transformed cells.
Dunbar, A.J. & Goddard, C. (2000) Int. J. Biochem. & Cell Biol. 32, 805-815. Groenen L. C. et al. (1994) Growth Factors, 11, 235-257 Source:Produced recombinantly in E.coli Purity:> 95 % (by HPLC and N-terminal sequence analysis) Molecular Weight:5546 daltons - confirmed by Mass Spectrometry N-terminal sequence analysis:5 residues > 95 % single sequence Biological Activity:Cell growth bioassay in Balb/c 3T3 fibroblasts: ED50 2.5 ng/ml EGF radioreceptor assay in AG2804 fibroblasts: ED50 10 ng/ml Endotoxin:< 0.1 EU/μg State and Appearance:Lyophilized white powder Dried from 0.1 M acetic acid and stored under nitrogen at a slight vacuum Storage/Stability:At least 2 years at 2 - 4°C (lyophilized)This is a Novozymes GroPep specification. ibt is authorized distributor of GroPep!