| Edit |   |
|---|
| Antigenic Specificity | MUC1 |
|---|
| Clone | SM3 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG2a |
|---|
| Format | fluorescein (FITC) conjugate |
|---|
| Size | 50ul |
|---|
| Concentration | 1mg/ml |
|---|
| Applications | Flow cyt, ICC/IF |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Mouse anti MUC1 [SM3]: Fluorescein. This antibody recognises mucin 1 (MUC1). MUC1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoitic cell lineages. In the vast majority of human carcinomas, this protein is upregulated, poorly glycosylated and appears on the cell surface in a non-polarised fashion. The SM3 antibody reacts with a core protein epitope defined as PDTRP. SM3 also detects MUC1 within colon and ovarian cancer and most adenocarcinomas. |
|---|
| Immunogen | Hydrogen fluoride deglycosylated milk mucin. |
|---|
| Other Names | Breast carcinoma-associated antigen DF3; Carcinoma-associated mucin; CD227; DF3 antigen; EMA; Episialin; H23 antigen; H23AG; KL-6; MAM6; MUC-1; MUC-1/SEC; MUC-1/X; MUC1; MUC1-alpha; MUC1-beta; MUC1-CT; MUC1-NT; MUC1/ZD; mucin 1, cell surface associated; mucin 1, transmembrane; Mucin-1; Mucin-1 subunit alpha; Mucin-1 subunit beta; Peanut-reactive urinary mucin; PEM; PEMT; Polymorphic epithelial mucin; PUM; tumor associated epithelial mucin; Tumor-associated epithelial membrane antigen; Tumor-associated mucin |
|---|
| Gene, Accession # | n/a |
|---|
| Catalog # | IQ636FITC |
|---|
| Price | |
|---|
| Order / More Info | MUC1 Antibody from IMMUQUEST LTD. |
|---|
| Product Specific References | Burchell J, et al. A short sequence, within the amino acid tandem repeat of a cancer-associated mucin, contains immunodominant epitopes. Int J Cancer.1989.44(4):691-6. PMID:2477336 http://www.ncbi.nlm.nih.gov/pubmed/2477336; Burchell J, et al. Development and characterization of breast cancer reactive monoclonal antibodies directed to the core protein of the human milk mucin. Cancer Res.1987. 47(20):5476-82. PMID:2443241 http://www.ncbi.nlm.nih.gov/pubmed/2443241 |
|---|