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Description
Rabbit Anti-Lamin C. This antibody reacts strongly in immunoblotting with fragments corresponding to peptide 319-572aa of Lamin C. When tested against nuclear protein extracts from HeLa cells it reacts with a single band migrating at 65 kDa
Immunogen
A peptide made from the last 8 amino acids of lamin C, including an N-terminal lysine as a linker (KHHVSGSRR), coupled to KLH
Expression of individual lamins in basal cell carcinomas of the skin. Venables, R.S. et al., British Journal of Cancer 2001, 84 (4), 512-519 PUBMED Lamin expression in normal human skin, actinic keratosis, squamous cell carcinoma and basal cell carcinoma. Tilli CM et al. Br J Dermatol. 2003 Jan;148(1):102-9 PUBMED Partial cleavage of A-type lamins concurs with their total disintegration from the nuclear lamina during apoptosis. Broers JL et al. Eur J Cell Biol. 2002 Dec;81(12):677-91 PUBMED Ikuta K et al. The Sp1 transcription factor is essential for the expression of gliostatin/thymidine phosphorylase in rheumatoid fibroblast-like synoviocytes. Arthritis Res Ther. 2012 Apr 25;14(2):R87. doi: 10.1186/ar3811. WB (Human)PMID: 22534375 Ostlund C et al. Lamin-associated proteins. Methods Cell Biol. 2004;78:829-59. ICC/IF (Rat) PMID: 15646641