Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:1000
Reviews / Ratings
If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description
ABCA4 Polyclonal Antibody. The ATP-binding cassette (ABC) superfamily is comprised of transmembrane proteins involved in energy-dependent transport of a variety of substrates across membranes. ABCA4 (also designated ABCR, photoreceptor RIM or RMP) is a photoreceptor specific ATP-binding cassette (ABC) transporter. ABCA4 is exclusively expressed within photoreceptor cells, indicating that ABCA4 mediates the transport of an essential molecule either into or out of photoreceptor cells. Mutations in the gene encoding ABCA4 are responsible for autosomal recessive Stargardt disease (STGD), an early onset macular degeneration, and some forms of autosomal recessive cone-rod dystrophy and autosomal recessive retinitis pigmentosa. In addition, hetero
Immunogen
n/a
Other Names
Retinal-specific ATP-binding cassette transporter; ATP-binding cassette sub-family A member 4; RIM ABC transporter; RIM protein; RmP; Stargardt disease protein; ABCA4; ABCR