TWEAKR belongs to the TNF family of transmembrane proteins and contains a cytoplasmic death domain, which can activated the cell's apoptotic machinery. It is expressed in the spleen, thymus, peripheral blood lymphocytes, colon, and small intestine. Signal transduction by TWEAKR can be activated by either the membrane anchored or the soluble TWEAK. Recombinant soluble TWEAKR is a 53 amino acid polypeptide (5.6 kDa) comprising the entire extracellular domain of the full length TWEAKR protein.
Size
Various Sizes
Concentration
n/a
Applications
Cell Culture
Other Names
Tumor necrosis factor receptor superfamily member 12A;Fibroblast growth factor-inducible immediate-early response protein 14;FGF-inducible 14;Tweak-receptor;TweakR;CD266;TNFRSF12A;FN14; TNF-related weak inducer of apoptosis receptor, TNFRSF12A, FGF-inducible 14