CCL3 is a chemokine belonging to the CC chemokine family. CCL3 is involved in activation and recruitment of lymphocytes, monocytes, and granulocytes during acute inflammation. In addition to regulating leukocyte migration, CCL3 enhances IFN-γ secretion from activated T cells and thus induces Th1 response. Moreover, CCL3 has been reported to be involved in susceptibility of HIV infection and disease progression of AIDS. Human CCL3 is also demonstrated to inhibit proliferation of hematopoietic progenitor stem cells.
Size
500 μg
Concentration
n/a
Applications
BA
Other Names
Macrophage inflammatory protein 1-alpha (MIP-1-alpha), LD78-alpha, SCYA3, G0S19-1