A potent PLD2 inhibitor, both in vitro (IC50 = 140 nM) and in cells (IC50 = 110 nM); also effective as a PLD1 inhibitor at higher concentrations (IC50 = 5.1 μM in vitro, 1.0 μM in cells); strongly inhibits the invasive migration of breast cancer cells in transwell assays
Size
1 mg
Concentration
n/a
Applications
n/a
Other Names
Phospholipase D PLDs PLD1 PLD2 phosphatidic acid PA inhibitors chemotaxis cells migration cancers breast cancer inhibition inhibited