If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description
CTCF (CCCTC-binding factor) is a highly conserved zinc finger protein which plays an important role in transcriptional activation/repression, insulation, imprinting, and X chromosome inactivation depending on the DNA context of the binding site. It contains a DNA-binding domain composed of 11 zinc-fingers and the DNA target sequences recognized by CTCF which are fairly long and strikingly diverse. CTCF can be phosphorylated by the protein kinase CK2, as well as poly(ADP-ribosyl)ated. The latter modification regulates its activity as a chromatin insulator.CTCF Antibody is developed in rabbit using a KLH-coupled synthetic peptide within residues 150-00 of human CTCF (Swiss Prot: P49711).
Immunogen
KLH-coupled synthetic peptide within AA 150-200 of human CTCF .