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Description
Lamin A/C(Ser22) Polyclonal Antibody, Biotin Conjugated. ? Target Background: Nuclear lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane. Two main subtypes of nuclear lamins can be distinguished, i.e. A type lamins and B type lamins. The A type lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e. lamin A, lamin C and lamin Adel 10, while the B type lamins include two proteins arising from two distinct genes, i.e. lamin B1 and lamin B2. Recent evidence has revealed that mutation
Immunogen
KLH conjugated synthetic phosphopeptide derived from human Lamin A/C around the phosphorylation site of Ser22