Purity >98% by NMR, TLC. Agonist at neuronal nicotinic acetylcholine receptors displaying the highest potency at a4b2 and a2b2 subtypes (EC50= approximately 6 and 11 uM, respectively). Displays anxiolytic activity in a rat model and was 6-fold more potent than diazepam. Reduces distractibility in a primate model and may have relevance in attention deficit hyperactivity disorder. Improves cognition in Alzheimer's disease patients.