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Description
DERLIN-1 Polyclonal Antibody, Cy7 Conjugated. ? Target Background: Degradation in endoplasmic reticulum proteins, also designated Derlins or DERtrins, are crucial for the degradation of misfolded endoplasmic reticulum (ER) luminal proteins. Derlin proteins are multi-pass membrane proteins localizing to the ER. Derlins are involved in transferring misfolded proteins from the ER to the cytosol, where the misfolded proteins are destroyed in an ubiquitin-dependent manner by the proteasome. In the case of cytomegalovirus infection, Derlin-1, as opposed to Derlins-2
Immunogen
KLH conjugated synthetic peptide derived from human DERLIN-1. Immunogen Range: 120-170/251
Other Names
Derlin1; Derlin1; Derlin 1; DER1; DER-1; DER 1; DERL1_HUMAN.